Background

Rifaximin is an antibiotic medication primarily used to treat certain gastrointestinal conditions.

1. Irritable Bowel Syndrome (IBS) with Diarrhea: Rifaximin helps alleviate symptoms like bloating, abdominal pain, and diarrhea.
2. Hepatic Encephalopathy (HE): Rifaximin reduces the risk of HE episodes in patients with liver disease by decreasing ammonia-producing gut bacteria.
3. Traveler’s Diarrhea: Rifaximin can prevent and treat traveler’s diarrhea caused by certain bacteria.

Description

Composition:

(Rifaximin Tablets 550 mg)

Indications:

  • Diarrhea associated with IBD / IBS
  • Hepatic Encephalopathy
  • Traveler’s Diarrhea
  • Controls SIBO (Small Intestinal Bacterial Overgrowth)
  • Adjuvant therapy in chronic treatment-resistant pouchitis
  • Cirrhotic infections
  • Functional Dyspepsia

Why REFABER?

  • Rifaximin is a non-systemic, broad-spectrum oral antibiotic that binds to the β-subunit of bacterial RNA polymerase, blocking RNA synthesis and bacterial growth.
  • Demonstrates both bactericidal and bacteriostatic
  • Provides clinically significant relief in patients with IBS-D.
  • In traveler’s diarrhea, rifaximin is as effective as ciprofloxacin in reducing duration of unformed stools.
  • Reduces recurrence risk in hepatic encephalopathy.
  • Approved for treatment of IBS-D in adults with well-established safety.
  • Effective as adjunctive therapy in Crohn’s disease and SIBO

Available Strengths:

  • REFABER 400 mg
  • REFABER 550 mg

Dosage & Administration:

Indication Recommended Dose
Traveler’s Diarrhea 400 mg three times daily for 3 days
IBS-D (Irritable Bowel Syndrome) 550 mg three times daily for 14 days (can retreat up to 2 times)
Hepatic Encephalopathy 550 mg twice daily

Dosage may vary at the discretion of the physician based on patient profile.

Packaging:

  • Available in Alu-Alu strips of 10 tablets
  • 400 mg and 550 mg strengths available

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