Background:

Acotif 300 contains Acotiamide Hydrochloride Hydrate, a first-in-class prokinetic agent and the world’s first approved treatment for Postprandial Distress Syndrome (PDS) — a key symptom cluster of Functional Dyspepsia (FD).

Description

Acotif 300 Tablets
(Sustained Release – 300 mg)

Indications

(In Functional Dyspepsia)

  • Postprandial fullness
  • Epigastric pain
  • Early satiety
  • Bloating after meals

Key Features:

  • Enhances gastric motility
  • Increases gastric contractions
  • Effective relief from PDS symptoms
  • Minimal side effects compared to conventional prokinetic drugs

Mechanism of Action:

Acotiamide improves gastric function through dual action:

  • Inhibition of muscarinic autoreceptors, enhancing acetylcholine release
  • Inhibition of acetylcholinesterase, prolonging acetylcholine activity in the stomach

These actions lead to better gastric emptying and symptom relief in functional dyspepsia.

Dosage & Administration:

  • Acotif 300 mg SR: Take once daily before meals or as prescribed by a healthcare professional.

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