Background

ROFUXA 500 is an oral antibiotic containing Cefuroxime Axetil, a broad-spectrum second-generation cephalosporin. It is effective against a wide range of gram-positive and gram-negative bacteria, including many β-lactamase–producing strains.

Description

ROFUXA 500 is an oral antibiotic containing Cefuroxime Axetil, a broad-spectrum second-generation cephalosporin. It is effective against a wide range of gram-positive and gram-negative bacteria, including many β-lactamase–producing strains.

COMPOSITION

Each film-coated tablet contains:

  • Cefuroxime Axetil IP … 500 mg

INDICATIONS

ROFUXA 500 is indicated for the treatment of the following infections:

  • Upper respiratory tract infections: Otitis media, sinusitis, tonsillitis, pharyngitis
  • Lower respiratory tract infections: Acute and chronic bronchitis, pneumonia
  • Genitourinary tract infections: Pyelonephritis, cystitis, urethritis, uncomplicated gonorrhea (urethritis and cervicitis)
  • Skin and soft tissue infections: Furunculosis, pyoderma, impetigo
  • Early Lyme disease: Including erythema marginatum
  • Bone and joint infections
  • Meningitis
  • Septicemia
  • Surgical prophylaxis: Abdominal, pelvic, orthopedic, cardiac, pulmonary, esophageal, and vascular procedures

MODE OF ACTION

Cefuroxime inhibits bacterial cell wall synthesis by blocking the transpeptidation process, leading to the formation of an imperfect cell wall and subsequent bacterial lysis and death.

DOSAGE & DURATION

Indication Dosage Duration
Acute bacterial exacerbations of chronic bronchitis 500 mg every 12 hours 10 days
Secondary bacterial infections of acute bronchitis 500 mg every 12 hours 5–10 days
Uncomplicated skin & skin structure infections 500 mg every 12 hours 10 days
Early Lyme disease 500 mg every 12 hours 20 days

Dosage should be based on the severity of infection, the causative organism, and patient response, or as directed by a Registered Medical Practitioner.

PRESENTATION

ROFUXA 500 Tablets are available in Alu-Alu strips of 10 tablets.

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