Background:
Cefuroxime Axetil 500 mg + Clavulanic Acid 125 mg, a broad-spectrum antibiotic combination used for treating moderate to severe bacterial infections, especially those resistant to ordinary cephalosporins or penicillins.
a) Cefuroxime Axetil – 500 mg
A second-generation cephalosporin antibiotic.
Mechanism: Inhibits bacterial cell wall synthesis, leading to cell death.
Effective against both Gram-positive and Gram-negative organisms.
Active against Streptococcus pneumoniae, Staphylococcus aureus (non-MRSA), E. coli, Klebsiella, Haemophilus influenzae, Neisseria, etc.
b) Clavulanic Acid – 125 mg
A β-lactamase inhibitor.
Protects cefuroxime from being broken down by β-lactamase-producing bacteria, thereby extending its spectrum.
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