Introduction

The common cold, allergic rhinitis, and upper respiratory tract infections (URTIs) are among the most frequent illnesses in children. These conditions are commonly associated with nasal congestion, runny nose, sneezing, watery eyes, nasal irritation, and difficulty breathing through the nose. Persistent nasal blockage can disturb sleep, reduce appetite, and affect the child’s overall comfort and daily activities.

Prompt symptomatic management helps relieve nasal obstruction, control allergy symptoms, and improve breathing comfort. A combination of a nasal decongestant and antihistamine provides effective relief from the most common symptoms of cold and allergic rhinitis.

RESPIBER AF SYRUP is a pediatric formulation containing Phenylephrine Hydrochloride and Chlorpheniramine Maleate, specially developed to relieve nasal congestion, sneezing, rhinorrhea, and other allergy-related symptoms in children.

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Description

RESPIBER AF SYRUP is a dual-action pediatric syrup formulated to provide rapid symptomatic relief from common cold and allergic rhinitis. The combination of Phenylephrine Hydrochloride, a nasal decongestant, and Chlorpheniramine Maleate, an antihistamine, helps reduce nasal swelling, relieve congestion, and control sneezing, runny nose, watery eyes, and nasal irritation, allowing children to breathe comfortably and recover faster.

Composition

Each 5 ml contains:

  • Phenylephrine Hydrochloride5 mg
  • Chlorpheniramine Maleate2 mg

Dosage Form: Oral Syrup

Indications

RESPIBER AF SYRUP is indicated for the symptomatic relief of:

  • Common cold
  • Allergic rhinitis
  • Seasonal allergies
  • Upper respiratory tract infections (URTIs)
  • Nasal congestion
  • Runny nose (Rhinorrhea)
  • Sneezing
  • Watery eyes
  • Nasal itching and irritation
  • Sinus congestion associated with cold

Mode of Action

The two active ingredients provide complementary actions for effective relief of nasal congestion and allergy symptoms.

Phenylephrine Hydrochloride

Phenylephrine is a selective α1-adrenergic receptor agonist that constricts the dilated blood vessels of the nasal mucosa. This reduces swelling and inflammation, relieves nasal congestion, and improves nasal airflow, making breathing easier.

Chlorpheniramine Maleate

Chlorpheniramine is a first-generation H1 antihistamine that blocks the effects of histamine released during allergic reactions. It effectively reduces sneezing, rhinorrhea, watery eyes, nasal itching, and other allergy-related symptoms.

Combined Action

The synergistic combination helps to:

  • Relieve nasal congestion
  • Reduce sneezing
  • Control runny nose
  • Reduce watery eyes
  • Minimize nasal irritation
  • Improve breathing comfort
  • Provide effective relief from cold and allergy symptoms

Dosage

Age Group Recommended Dose
2–6 Years 5 mL twice daily (BID)
6–12 Years 5–10 mL twice daily (BID)

Clinical Benefits

  • Provides effective relief from nasal congestion by reducing swelling of the nasal passages.
  • Helps relieve runny nose, sneezing, and watery eyes associated with allergic rhinitis and the common cold.
  • Promotes easier breathing by clearing blocked nasal passages.
  • Offers symptomatic relief from upper respiratory tract allergies and cold-related discomfort.
  • Combines a nasal decongestant and an antihistamine for comprehensive allergy and cold symptom management.
  • Suitable for reducing discomfort caused by seasonal allergies and common cold symptoms.

Administration

  • Shake well before use.
  • Administer orally using the provided measuring cup or dosing spoon.
  • Use the prescribed dose as directed by the physician.
  • May be administered with or without food.
  • Do not exceed the recommended dosage.
  • Store in a cool and dry place away from direct sunlight.
  • Keep out of reach of children.

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