Introduction

BERACT 625 is a broad-spectrum antibiotic combining Amoxycillin and Clavulanate Potassium. It is indicated for the treatment of mild to severe bacterial infections caused by susceptible organisms, including β-lactamase-producing bacteria. The combination provides enhanced antibacterial coverage and helps overcome bacterial resistance.

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Description

BERACT 625 Tablet contains Amoxycillin 500 mg and Clavulanate Potassium 125 mg. It is commonly prescribed for adults and adolescents to treat respiratory tract infections, urinary tract infections, skin and soft tissue infections, dental infections, and other bacterial infections.

Composition

Each film-coated tablet contains:

  • Amoxycillin500 mg
  • Clavulanate Potassium125 mg

Indications

  • Acute Bacterial Sinusitis
  • Acute Otitis Media
  • Tonsillitis & Pharyngitis
  • Community-Acquired Pneumonia
  • Acute Exacerbation of Chronic Bronchitis
  • Skin & Soft Tissue Infections
  • Urinary Tract Infections (UTIs)
  • Dental Abscess and Dental Infections
  • Bone & Joint Infections
  • Other infections caused by susceptible bacteria

Mode of Action

  • Amoxycillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, causing bacterial cell death.
  • Clavulanate Potassium inhibits β-lactamase enzymes produced by resistant bacteria, protecting amoxycillin from degradation.
  • The combination provides synergistic, broad-spectrum bactericidal activity against susceptible Gram-positive and Gram-negative organisms.

Dosage

Patient Group Recommended Dose
Patients weighing >40 kg 1 tablet twice or three times daily

Adults and adolescents:

  • In severe infections, the dose may be adjusted according to clinical judgment.
  • Complete the entire prescribed course to ensure effective treatment and reduce the risk of antimicrobial resistance.

Clinical Benefits

  • Broad-spectrum antibacterial coverage against Gram-positive and Gram-negative bacteria.
  • Effective against β-lactamase-producing organisms due to the presence of Clavulanate Potassium.
  • High clinical cure rates in respiratory tract, ENT, urinary tract, skin & soft tissue, and dental infections.
  • Rapid symptom relief by reducing bacterial load and controlling infection.
  • Twice-daily dosing improves patient compliance and treatment adherence.
  • Reduces treatment failure associated with amoxycillin alone in resistant bacterial infections.
  • Well-established safety and efficacy, making it a trusted choice in routine clinical practice.
  • Helps prevent complications by ensuring complete eradication of susceptible pathogens when taken as prescribed.

Administration

  1. Take the tablet at the beginning of a meal to improve absorption and reduce gastrointestinal discomfort.
  2. Swallow the tablet whole with a glass of water.
  3. Do not skip doses or stop treatment early, even if symptoms improve.
  4. Maintain the prescribed dosing interval for optimal therapeutic effect.
  5. Store in a cool, dry place away from moisture and direct sunlight.

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