Description
COFBRICK LS SYRUP is a triple-action respiratory formulation designed for the management of productive cough associated with bronchospasm and excessive mucus secretion. It combines the bronchodilator action of Levosalbutamol, the mucolytic effect of Ambroxol, and the expectorant property of Guaiphenesin to facilitate mucus clearance, improve airflow, and relieve respiratory discomfort.
Composition
Each 5 ml contains:
- Levosalbutamol Sulphate equivalent to Levosalbutamol – 1 mg
- Ambroxol Hydrochloride – 30 mg
- Guaiphenesin – 50 mg
Dosage Form: Oral Syrup
Indications
COFBRICK LS SYRUP is indicated for:
- Productive cough
- Acute bronchitis
- Chronic bronchitis
- Bronchial asthma with productive cough
- Chronic Obstructive Pulmonary Disease (COPD)
- Lower respiratory tract infections associated with mucus production
- Chest congestion
- Wheezing associated with bronchospasm
- Respiratory conditions requiring bronchodilation and mucus clearance
Mode of Action
The three active ingredients work synergistically to relieve cough, clear mucus, and improve breathing.
Levosalbutamol
Levosalbutamol is a selective β2-adrenergic agonist that relaxes the smooth muscles of the bronchial airways, producing rapid bronchodilation. It relieves bronchospasm, reduces airway resistance, and improves airflow, thereby easing breathing.
Ambroxol Hydrochloride
Ambroxol is a potent mucolytic agent that breaks down thick, sticky mucus into a thinner consistency. It enhances mucociliary clearance, facilitating the removal of respiratory secretions from the airways.
Guaiphenesin
Guaiphenesin acts as an expectorant by increasing the volume and reducing the viscosity of bronchial secretions. This promotes productive coughing and assists in the effective clearance of mucus from the respiratory tract.
Combined Action
The combination provides comprehensive relief by:
- Relieving bronchospasm
- Liquefying thick mucus
- Enhancing mucus clearance
- Improving airflow
- Reducing chest congestion
- Relieving productive cough
Dosage
| Age Group | Recommended Dose |
|---|---|
| 2–6 Years | 2.5–5 mL three times daily (TID) |
Clinical Benefits
- Provides triple-action relief from productive (wet) cough.
- Levosalbutamol relaxes bronchial smooth muscles, relieving bronchospasm and wheezing.
- Ambroxol breaks down thick, sticky mucus, making it easier to expel.
- Guaiphenesin increases respiratory secretions and facilitates mucus clearance.
- Improves airway patency, promoting easier breathing.
- Reduces cough frequency by clearing mucus from the airways.
- Provides effective relief in bronchitis, lower respiratory tract infections, and mucus-associated cough.
- Enhances mucociliary clearance, helping remove mucus and trapped pathogens.
- Reduces chest congestion and improves patient comfort.
Administration
- Shake well before use.
- Administer orally using the provided measuring cup.
- Take the prescribed dose after meals or as directed by the physician.
- Drink adequate fluids during therapy to support mucus clearance.
- Store in a cool and dry place, protected from direct sunlight.
- Keep out of reach of children.
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