Introduction

Syrup :- Levocetirizine Hydrochloride 2.5 mg + Montelukast Sodium 4 mg per 5 ml

Tablet :- Levocetirizine Hydrochloride 5 mg + Montelukast Sodium 10 mg

Allergic disorders such as allergic rhinitis, seasonal allergies, perennial allergies, and allergic cough are increasingly common in both children and adults. Exposure to allergens like pollen, dust mites, pet dander, mold, and environmental pollutants can trigger symptoms including sneezing, runny nose, nasal congestion, itching, watery eyes, and persistent cough. In susceptible individuals, these conditions may also aggravate asthma symptoms and reduce quality of life.

Effective allergy management requires controlling both the histamine-mediated allergic response and the leukotriene-mediated inflammatory pathway. Combining an antihistamine with a leukotriene receptor antagonist offers superior symptom control and helps prevent recurrence of allergic episodes.

ALENZA M combines Levocetirizine Hydrochloride, a potent second-generation antihistamine, with Montelukast Sodium, a leukotriene receptor antagonist, to provide comprehensive and long-lasting relief from allergic conditions in both pediatric and adult patients.

Category:

Description

ALENZA M is a dual-action anti-allergic formulation available as Syrup and Tablets. It effectively relieves symptoms of allergic rhinitis, seasonal allergies, perennial allergic rhinitis, and allergic cough by blocking both histamine and leukotriene pathways. The combination helps reduce nasal congestion, sneezing, itching, rhinorrhea, watery eyes, and airway inflammation while improving overall respiratory comfort.

Composition

ALENZA M Syrup

Each 5 ml contains:

  • Levocetirizine Hydrochloride2.5 mg
  • Montelukast SodiumEquivalent to Montelukast 4 mg

ALENZA M Tablet

Each tablet contains:

  • Levocetirizine Hydrochloride5 mg
  • Montelukast SodiumEquivalent to Montelukast 10 mg

Indications

ALENZA M is indicated for:

  • Seasonal allergic rhinitis
  • Perennial allergic rhinitis
  • Allergic cough
  • Allergic bronchitis
  • Dust allergy
  • Pollen allergy
  • Pet allergy
  • Sneezing
  • Runny nose (Rhinorrhea)
  • Nasal congestion
  • Nasal itching
  • Watery eyes
  • Chronic urticaria (Hives)
  • Adjunct therapy in allergic asthma (as prescribed)

Mode of Action

The two active ingredients work synergistically to provide complete allergy control.

Levocetirizine Hydrochloride

Levocetirizine is a second-generation selective H1-antihistamine that blocks peripheral histamine H1 receptors. It effectively relieves symptoms such as:

  • Sneezing
  • Runny nose
  • Nasal itching
  • Watery eyes
  • Skin itching and urticaria

Because of its high receptor selectivity, it provides effective allergy relief with minimal sedation in most patients.

Montelukast Sodium

Montelukast is a selective leukotriene receptor antagonist that blocks cysteinyl leukotriene (CysLT1) receptors. Leukotrienes are inflammatory mediators responsible for:

  • Airway inflammation
  • Bronchoconstriction
  • Nasal congestion
  • Mucosal swelling
  • Increased mucus production

By inhibiting leukotriene activity, Montelukast helps improve nasal airflow, reduces inflammation, and supports long-term allergy control.

Combined Action

The synergistic combination helps to:

  • Control immediate allergic reactions
  • Reduce nasal congestion
  • Relieve sneezing and runny nose
  • Reduce itching and watery eyes
  • Improve breathing comfort
  • Decrease airway inflammation
  • Help prevent recurrent allergy symptoms

Dosage

For Syrup :-

Age Group Recommended Dose
2–6 Years 5 mL once daily (OD)

For Tablet :-

As directed by the Registered Medical Practitioner.

Clinical Benefits

  • Provides dual-action relief from allergic rhinitis by combining an antihistamine with a leukotriene receptor antagonist.
  • Effectively relieves sneezing, runny nose, nasal congestion, and itching associated with allergies.
  • Helps reduce watery, itchy eyes caused by seasonal and perennial allergies.
  • Assists in controlling allergy-induced cough and upper airway inflammation.
  • Helps prevent allergy-triggered wheezing and supports better respiratory comfort in susceptible patients.
  • Offers 24-hour symptom control with convenient once-daily dosing (as prescribed).
  • Improves overall quality of life by reducing recurrent allergy symptoms and promoting uninterrupted daily activities and sleep.

Administration

  • Take exactly as prescribed by the physician.
  • Syrup: Shake well before use and administer using the provided measuring cup or spoon.
  • Tablet: Swallow whole with water; do not crush or chew unless advised.
  • May be taken with or without food.
  • Taking the medicine in the evening may provide better control of nighttime allergy symptoms, if recommended by the physician.
  • Complete the prescribed course for optimal symptom control.

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